Restylane Refyne is a popular injectable filler used to treat moderate to severe “laugh lines” around the mouth. It is made of hyaluronic acid, a natural substance found in the skin, and is FDA-approved for the treatment of wrinkles and folds. Restylane Refyne is commonly used to reduce the appearance of nasolabial folds, puppet lines, and other wrinkles around the nose and mouth. Results can last up to 12 months.
Restylane Refyne is designed to soften expression lines and maintain facial expressions and movement through Xpreshan technology. It is the only filler on the market that has been clinically proven to help maintain movement and expressions. The unique gel crosslink in Restylane Refyne also helps support natural expression and get real-life results that maintain natural movement when you smile, frown, or even frown. Restylane Defyne can also be used for deeper nasolabial folds, also known as “laugh lines”, as well as puppet lines from the corners of the mouth to the chin.
The most common side effects after Restylane Refyne include pain during injection, swelling at the placement site, or bruising. In addition, due to its filling structure, Restylane Refyne can provide longer wear and allow for less swelling than some previous fillers used to reduce wrinkles. Subjects were evaluated based on perceived naturalness of moving facial expressions after 1 month of optimal treatment with Restylane Refyne and Restylane Defyne. While there are other fillers on the market that can fill in wrinkles, Refyne and Defyne are intended to give a more natural-looking result than previously thought possible.
Every time you laugh, cry or frown, Refyne and Defyne facial fillers will continue to look soft and natural instead of stiff and puffy. Restylane Defyne is usually ideal for this area due to its advanced XpressHan formulation, which provides greater support and is generally more flexible than conventional hyaluronic acid-based fillers.